San Francisco 49ers @ Kansas City Chiefs — Prediction & Odds, NFL Week 16 2026

Sunday, December 27, 2026 · 3:25 PM CT · GEHA Field at Arrowhead Stadium

Game preview

The market makes Kansas City Chiefs a 3-point favourite over San Francisco 49ers, with the game total at 46.5.

Moneylines sit at +130 for San Francisco 49ers and -155 for Kansas City Chiefs, a devigged 58% win probability for Kansas City Chiefs; splitting the spread and total leaves market-implied team totals of 21.8 for San Francisco 49ers and 24.8 for Kansas City Chiefs.

The Sport Stack's nflsim engine projects San Francisco 49ers — Brock Purdy (QB) at 221 passing yards and 17 rushing yards, Christian McCaffrey (RB) at 46 rushing yards and 35 receiving yards; Kansas City Chiefs — Patrick Mahomes (QB) at 224 passing yards and 21 rushing yards, Kenneth Walker III (RB) at 78 rushing yards and 31 receiving yards.

Kickoff is Sunday, December 27, 2026 · 3:25 PM CT, at GEHA Field at Arrowhead Stadium, San Francisco 49ers take the extra rest, 10 days to 6.

New to these numbers? How devigging turns a price into a probability, how sportsbooks set these lines, what expected value means, and why to shop the number.

Consensus market (intraday)

Consensus market for 49ers at Chiefs — lines as of Thu, 9/10 · 7:01 PM CT
MarketConsensus
SpreadKC -3
Total46.5
Moneyline (SF / KC)+130 / -155
KC implied win probability58%
Implied team totals (SF — KC)21.8 — 24.8

Devigged cross-book consensus, updated as lines move. See the power ratings for the model's implied line on any matchup.

Player projections

San Francisco 49ers · 21.8 proj pts
Brock Purdy (QB) — 221 pass yds · 17 rush yds
Christian McCaffrey (RB) — 46 rush yds · 35 rec yds
Deebo Samuel Sr. (WR) — 5 rush yds · 39 rec yds
Kansas City Chiefs · 24.8 proj pts
Patrick Mahomes (QB) — 224 pass yds · 21 rush yds
Kenneth Walker III (RB) — 78 rush yds · 31 rec yds
Rashee Rice (WR) — 1 rush yds · 47 rec yds

Research context, not a pick — every staked play is graded on the public ledger. How we grade.

Go deeper

The interactive matchup dashboard adds usage cores, opponent-defense-vs-position strips, offense identity, and the multi-book open→close board for this game. Forecast conditions are on the NFL slate.

More Week 16 games

← Week 15 · Week 17 → · Full 2026 schedule