San Francisco 49ers @ Los Angeles Chargers — Prediction & Odds, NFL Week 15 2026

Thursday, December 17, 2026 · 7:15 PM CT · SoFi Stadium (indoors)

Game preview

The market makes Los Angeles Chargers a 2.5-point favourite over San Francisco 49ers, with the game total at 47.5.

Moneylines sit at +120 for San Francisco 49ers and -142 for Los Angeles Chargers, a devigged 56% win probability for Los Angeles Chargers; splitting the spread and total leaves market-implied team totals of 22.5 for San Francisco 49ers and 25 for Los Angeles Chargers.

The Sport Stack's nflsim engine projects San Francisco 49ers — Brock Purdy (QB) at 228 passing yards and 17 rushing yards, Christian McCaffrey (RB) at 49 rushing yards and 33 receiving yards; Los Angeles Chargers — Justin Herbert (QB) at 201 passing yards and 20 rushing yards, Omarion Hampton (RB) at 68 rushing yards and 12 receiving yards.

Kickoff is Thursday, December 17, 2026 · 7:15 PM CT, at SoFi Stadium, indoors.

New to these numbers? How devigging turns a price into a probability, how sportsbooks set these lines, what expected value means, and why to shop the number.

Consensus market (intraday)

Consensus market for 49ers at Chargers — lines as of Thu, 9/10 · 7:01 PM CT
MarketConsensus
SpreadLAC -2.5
Total47.5
Moneyline (SF / LAC)+120 / -142
LAC implied win probability56%
Implied team totals (SF — LAC)22.5 — 25.0

Devigged cross-book consensus, updated as lines move. See the power ratings for the model's implied line on any matchup.

Player projections

San Francisco 49ers · 22.5 proj pts
Brock Purdy (QB) — 228 pass yds · 17 rush yds
Christian McCaffrey (RB) — 49 rush yds · 33 rec yds
Deebo Samuel Sr. (WR) — 5 rush yds · 43 rec yds
Los Angeles Chargers · 25.0 proj pts
Justin Herbert (QB) — 201 pass yds · 20 rush yds
Omarion Hampton (RB) — 68 rush yds · 12 rec yds
Ladd McConkey (WR) — 49 rec yds · 3.9 rec

Research context, not a pick — every staked play is graded on the public ledger. How we grade.

Go deeper

The interactive matchup dashboard adds usage cores, opponent-defense-vs-position strips, offense identity, and the multi-book open→close board for this game. Forecast conditions are on the NFL slate.

More Week 15 games

← Week 14 · Week 16 → · Full 2026 schedule