Minnesota Vikings @ San Francisco 49ers — Prediction & Odds, NFL Week 11 2026

Sunday, November 22, 2026 · 8:20 PM ET · Estadio Banorte · neutral site

Prediction: 49ers 25, Vikings 21 (market-implied). The market gives the San Francisco 49ers a 65% chance to win. · Updated

The full matchup dashboard

Free: prime time

Every angle of Vikings @ 49ers, on one screen.

Vikings21.0win 35%
Market-implied score
49ers24.5win 65%
SpreadSF -3.5
Total45.5
Moneyline+175 / -211
  • The market-implied score next to the spread and total
  • Player projections against their prop lines, with the best price
  • What decides it: each passing matchup, protection and pace
  • Who is out and how much they play, and the best price on every side
Open the full matchup →Prime time · open to everyone

Vikings vs 49ers prediction

The market makes San Francisco 49ers a 3.5-point favorite over Minnesota Vikings, with the game total at 45.5.

Moneylines sit at +175 for Minnesota Vikings and -211 for San Francisco 49ers, a devigged 65% win probability for San Francisco 49ers; splitting the spread and total leaves market-implied team totals of 21 for Minnesota Vikings and 24.5 for San Francisco 49ers.

The total has moved from 46.5 to 45.5.

The Sport Stack's nflsim engine projects Minnesota Vikings — Carson Wentz (QB) at 200 passing yards and 11 rushing yards, Justin Jefferson (WR) at 1 rushing yards and 62 receiving yards; San Francisco 49ers — Brock Purdy (QB) at 231 passing yards and 19 rushing yards, Christian McCaffrey (RB) at 52 rushing yards and 29 receiving yards.

Kickoff is Sunday, November 22, 2026 · 8:20 PM ET, at Estadio Banorte, a neutral site.

New to these numbers? How devigging turns a price into a probability, how sportsbooks set these lines, what expected value means, and why to shop the number.

Consensus market

Consensus market for Vikings at 49ers — lines as of Tue, 11/10 · 9:02 PM ET
MarketConsensus
SpreadSF -3.5
Total45.5 (open 46.5)
Moneyline (MIN / SF)+175 / -211
SF implied win probability65%
Implied team totals (MIN — SF)21.0 — 24.5

Devigged cross-book consensus, updated as lines move. See the power ratings for the model's implied line on any matchup.

Vikings and 49ers this season

Games before Week 11. Against the spread and over/under are graded against the consensus line.
TeamRecordAgainst the spreadOver/underPoints forPoints againstDays of rest
Minnesota Vikings6-24-41-718.314.57
San Francisco 49ers7-15-34-429.419.57

Vikings' last 3 games: L 6-23 vs BUF · L 15-19 @ DET · W 16-10 vs IND.

49ers' last 3 games: W 38-17 vs LV · L 20-29 @ ATL · W 23-17 vs WAS.

Player projections

Minnesota Vikings · 21.0 market-implied pts
Carson Wentz (QB) — 200 pass yds · 11 rush yds
Justin Jefferson (WR) — 1 rush yds · 62 rec yds
Jordan Mason (RB) — 45 rush yds · 7 rec yds
San Francisco 49ers · 24.5 market-implied pts
Brock Purdy (QB) — 231 pass yds · 19 rush yds
Christian McCaffrey (RB) — 52 rush yds · 29 rec yds
Mike Evans (WR) — 52 rec yds · 4.1 rec

Research context, not a pick — every staked play is graded on the public ledger. How we grade.

What decides Vikings @ 49ers, who is out and how much they play, the best price on every side, and every book's number.

Open the Vikings @ 49ers matchup →

Kickoff weather and conditions are on the NFL slate.

More Week 11 games

← Week 10 · Week 12 → · Full 2026 schedule

Vikings 2026 schedule

49ers 2026 schedule