Los Angeles Rams @ San Francisco 49ers — Prediction & Odds, NFL Week 14 2026

Sunday, December 13, 2026 · 4:25 PM ET · Levi's Stadium

Prediction: Rams 26, 49ers 24 (market-implied). The market gives the Los Angeles Rams a 56% chance to win. · Updated

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Every angle of Rams @ 49ers, on one screen.

Rams26.0win 56%
Market-implied score
49ers24.0win 44%
SpreadLA -2
Total50
Moneyline-139 / +115
  • The market-implied score next to the spread and total
  • Player projections against their prop lines, with the best price
  • What decides it: each passing matchup, protection and pace
  • Who is out and how much they play, and the best price on every side
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Rams vs 49ers prediction

The market makes Los Angeles Rams a 2-point favorite over San Francisco 49ers, with the game total at 50.

Moneylines sit at -139 for Los Angeles Rams and +115 for San Francisco 49ers, a devigged 44% win probability for San Francisco 49ers; splitting the spread and total leaves market-implied team totals of 26 for Los Angeles Rams and 24 for San Francisco 49ers.

The spread has moved from LA -2.5 to LA -2 since it opened.

The Sport Stack's nflsim engine projects Los Angeles Rams — Matthew Stafford (QB) at 226 passing yards and 3 rushing yards, Puka Nacua (WR) at 4 rushing yards and 95 receiving yards; San Francisco 49ers — Brock Purdy (QB) at 247 passing yards and 20 rushing yards, Christian McCaffrey (RB) at 49 rushing yards and 33 receiving yards.

Kickoff is Sunday, December 13, 2026 · 4:25 PM ET, at Levi's Stadium, Los Angeles Rams take the extra rest, 10 days to 7.

New to these numbers? How devigging turns a price into a probability, how sportsbooks set these lines, what expected value means, and why to shop the number.

Consensus market

Consensus market for Rams at 49ers — lines as of Thu, 9/10 · 8:01 PM ET
MarketConsensus
SpreadLA -2 (open LA -2.5)
Total50
Moneyline (LA / SF)-139 / +115
SF implied win probability44%
Implied team totals (LA — SF)26.0 — 24.0

Devigged cross-book consensus from the latest snapshot we hold, dated above. See the power ratings for the model's implied line on any matchup.

Rams and 49ers this season

Games before Week 14. Against the spread and over/under are graded against the consensus line.
TeamRecordAgainst the spreadOver/underPoints forPoints againstDays of rest
Los Angeles Rams5-45-44-523.820.110
San Francisco 49ers7-15-34-429.419.57

Rams' last 3 games: W 20-13 @ WAS · W 24-9 vs LAC · W 35-21 @ LV.

49ers' last 3 games: W 38-17 vs LV · L 20-29 @ ATL · W 23-17 vs WAS.

Player projections

Los Angeles Rams · 26.0 market-implied pts
Matthew Stafford (QB) — 226 pass yds · 3 rush yds
Puka Nacua (WR) — 4 rush yds · 95 rec yds
Kyren Williams (RB) — 56 rush yds · 18 rec yds
San Francisco 49ers · 24.0 market-implied pts
Brock Purdy (QB) — 247 pass yds · 20 rush yds
Christian McCaffrey (RB) — 49 rush yds · 33 rec yds
Mike Evans (WR) — 55 rec yds · 4.2 rec

Research context, not a pick — every staked play is graded on the public ledger. How we grade.

What decides Rams @ 49ers, who is out and how much they play, the best price on every side, and every book's number.

Open the Rams @ 49ers matchup →

Kickoff weather and conditions are on the NFL slate.

More Week 14 games

← Week 13 · Week 15 → · Full 2026 schedule

Rams 2026 schedule

49ers 2026 schedule