Arizona Cardinals @ Los Angeles Rams — Prediction & Odds, NFL Week 6 2026

Sunday, October 18, 2026 · 3:05 PM CT · SoFi Stadium (indoors)

Game preview

The market makes Los Angeles Rams a 13.5-point favourite over Arizona Cardinals, with the game total at 47.5.

Moneylines sit at +525 for Arizona Cardinals and -750 for Los Angeles Rams, a devigged 85% win probability for Los Angeles Rams; splitting the spread and total leaves market-implied team totals of 17 for Arizona Cardinals and 30.5 for Los Angeles Rams.

The Sport Stack's nflsim engine projects Arizona Cardinals — Jacoby Brissett (QB) at 215 passing yards and 12 rushing yards, Trey McBride (TE) at 63 receiving yards and 6.3 catches; Los Angeles Rams — Matthew Stafford (QB) at 216 passing yards and 2 rushing yards, Kyren Williams (RB) at 68 rushing yards and 17 receiving yards.

Kickoff is Sunday, October 18, 2026 · 3:05 PM CT, at SoFi Stadium, indoors.

New to these numbers? How devigging turns a price into a probability, how sportsbooks set these lines, what expected value means, and why to shop the number.

Consensus market (intraday)

Consensus market for Cardinals at Rams — lines as of Thu, 9/10 · 7:01 PM CT
MarketConsensus
SpreadLA -13.5
Total47.5
Moneyline (ARI / LA)+525 / -750
LA implied win probability85%
Implied team totals (ARI — LA)17.0 — 30.5

Devigged cross-book consensus, updated as lines move. See the power ratings for the model's implied line on any matchup.

Player projections

Arizona Cardinals · 16.8 proj pts
Jacoby Brissett (QB) — 215 pass yds · 12 rush yds
Trey McBride (TE) — 63 rec yds · 6.3 rec
Jeremiyah Love (RB) — 44 rush yds · 19 rec yds
Los Angeles Rams · 30.8 proj pts
Matthew Stafford (QB) — 216 pass yds · 2 rush yds
Kyren Williams (RB) — 68 rush yds · 17 rec yds
Puka Nacua (WR) — 2 rush yds · 79 rec yds

Research context, not a pick — every staked play is graded on the public ledger. How we grade.

Go deeper

The interactive matchup dashboard adds usage cores, opponent-defense-vs-position strips, offense identity, and the multi-book open→close board for this game. Forecast conditions are on the NFL slate.

More Week 6 games

← Week 5 · Week 7 → · Full 2026 schedule