Tennessee Titans @ Indianapolis Colts — Prediction & Odds, NFL Week 6 2026

Sunday, October 18, 2026 · 12:00 PM CT · Lucas Oil Stadium (retractable roof)

Game preview

The market makes Indianapolis Colts a 3.5-point favourite over Tennessee Titans, with the game total at 47.5.

Moneylines sit at +160 for Tennessee Titans and -192 for Indianapolis Colts, a devigged 63% win probability for Indianapolis Colts; splitting the spread and total leaves market-implied team totals of 22 for Tennessee Titans and 25.5 for Indianapolis Colts.

The Sport Stack's nflsim engine projects Tennessee Titans — Cam Ward (QB) at 209 passing yards and 13 rushing yards, Tony Pollard (RB) at 51 rushing yards and 12 receiving yards; Indianapolis Colts — Daniel Jones (QB) at 232 passing yards and 14 rushing yards, Jonathan Taylor (RB) at 81 rushing yards and 21 receiving yards.

Kickoff is Sunday, October 18, 2026 · 12:00 PM CT, at Lucas Oil Stadium, indoors.

New to these numbers? How devigging turns a price into a probability, how sportsbooks set these lines, what expected value means, and why to shop the number.

Consensus market (intraday)

Consensus market for Titans at Colts — lines as of Sun, 9/13 · 12:16 PM CT
MarketConsensus
SpreadIND -3.5
Total47.5
Moneyline (TEN / IND)+160 / -192
IND implied win probability63%
Implied team totals (TEN — IND)22.0 — 25.5

Devigged cross-book consensus, updated as lines move. See the power ratings for the model's implied line on any matchup.

Player projections

Tennessee Titans · 22.3 proj pts
Cam Ward (QB) — 209 pass yds · 13 rush yds
Tony Pollard (RB) — 51 rush yds · 12 rec yds
Carnell Tate (WR) — 47 rec yds · 3.6 rec
Indianapolis Colts · 25.8 proj pts
Daniel Jones (QB) — 232 pass yds · 14 rush yds
Jonathan Taylor (RB) — 81 rush yds · 21 rec yds
Josh Downs (WR) — 50 rec yds · 4.2 rec

Research context, not a pick — every staked play is graded on the public ledger. How we grade.

Go deeper

The interactive matchup dashboard adds usage cores, opponent-defense-vs-position strips, offense identity, and the multi-book open→close board for this game. Forecast conditions are on the NFL slate.

More Week 6 games

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