Arizona Cardinals @ New Orleans Saints — Prediction & Odds, NFL Week 16 2026

Sunday, December 27, 2026 · 1:00 PM ET · Caesars Superdome (indoors)

Prediction: Saints 25, Cardinals 20 (market-implied). The market gives the New Orleans Saints a 68% chance to win. · Updated

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Every angle of Cardinals @ Saints, on one screen.

Cardinals19.5win 32%
Market-implied score
Saints25.0win 68%
SpreadNO -5.5
Total44.5
Moneyline+200 / -245
  • The market-implied score next to the spread and total
  • Player projections against their prop lines, with the best price
  • What decides it: each passing matchup, protection and pace
  • Who is out and how much they play, and the best price on every side
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Cardinals vs Saints prediction

The market makes New Orleans Saints a 5.5-point favorite over Arizona Cardinals, with the game total at 44.5.

Moneylines sit at +200 for Arizona Cardinals and -245 for New Orleans Saints, a devigged 68% win probability for New Orleans Saints; splitting the spread and total leaves market-implied team totals of 19.5 for Arizona Cardinals and 25 for New Orleans Saints.

The total has moved from 44 to 44.5.

The Sport Stack's nflsim engine projects Arizona Cardinals — Gardner Minshew (QB) at 241 passing yards and 7 rushing yards, Tyler Allgeier (RB) at 53 rushing yards and 18 receiving yards; New Orleans Saints — Tyler Shough (QB) at 231 passing yards and 17 rushing yards, Alvin Kamara (RB) at 44 rushing yards and 25 receiving yards.

Kickoff is Sunday, December 27, 2026 · 1:00 PM ET, at Caesars Superdome, indoors.

New to these numbers? How devigging turns a price into a probability, how sportsbooks set these lines, what expected value means, and why to shop the number.

Consensus market

Consensus market for Cardinals at Saints — lines as of Sun, 9/13 · 1:16 PM ET
MarketConsensus
SpreadNO -5.5
Total44.5 (open 44)
Moneyline (ARI / NO)+200 / -245
NO implied win probability68%
Implied team totals (ARI — NO)19.5 — 25.0

Devigged cross-book consensus from the latest snapshot we hold, dated above. See the power ratings for the model's implied line on any matchup.

Cardinals and Saints this season

Games before Week 16. Against the spread and over/under are graded against the consensus line.
TeamRecordAgainst the spreadOver/underPoints forPoints againstDays of rest
Arizona Cardinals3-64-55-419.828.37
New Orleans Saints3-53-55-323.127.07

Cardinals' last 3 games: L 3-17 @ SEA · W 33-30 @ DAL · L 16-30 vs DEN.

Saints' last 3 games: W 23-22 vs CLE · L 10-16 vs PIT · W 34-27 @ NYG.

Player projections

Arizona Cardinals · 19.5 market-implied pts
Gardner Minshew (QB) — 241 pass yds · 7 rush yds
Tyler Allgeier (RB) — 53 rush yds · 18 rec yds
Trey McBride (TE) — 71 rec yds · 7.7 rec
New Orleans Saints · 25.0 market-implied pts
Tyler Shough (QB) — 231 pass yds · 17 rush yds
Alvin Kamara (RB) — 44 rush yds · 25 rec yds
Chris Olave (WR) — 68 rec yds · 5.5 rec

Research context, not a pick — every staked play is graded on the public ledger. How we grade.

What decides Cardinals @ Saints, who is out and how much they play, the best price on every side, and every book's number.

Open the Cardinals @ Saints matchup →

Played indoors, so weather is not a factor. Every game's conditions are on the NFL slate.

More Week 16 games

← Week 15 · Week 17 → · Full 2026 schedule

Cardinals 2026 schedule

Saints 2026 schedule