Seattle Seahawks @ San Francisco 49ers — Prediction & Odds, NFL Week 12 2026

Sunday, November 29, 2026 · 3:25 PM CT · Levi's Stadium

Game preview

The market makes Seattle Seahawks a 1.5-point favourite over San Francisco 49ers, with the game total at 46.5.

Moneylines sit at -110 for Seattle Seahawks and -110 for San Francisco 49ers, a devigged 50% win probability for San Francisco 49ers; splitting the spread and total leaves market-implied team totals of 24 for Seattle Seahawks and 22.5 for San Francisco 49ers.

The spread has moved from -1.5 to 1.5 since it opened.

The Sport Stack's nflsim engine projects Seattle Seahawks — Drew Lock (QB) at 192 passing yards and 9 rushing yards, Jaxon Smith-Njigba (WR) at 1 rushing yards and 83 receiving yards; San Francisco 49ers — Brock Purdy (QB) at 229 passing yards and 17 rushing yards, Christian McCaffrey (RB) at 44 rushing yards and 37 receiving yards.

Kickoff is Sunday, November 29, 2026 · 3:25 PM CT, at Levi's Stadium, Seattle Seahawks take the extra rest, 14 days to 7.

New to these numbers? How devigging turns a price into a probability, how sportsbooks set these lines, what expected value means, and why to shop the number.

Consensus market (intraday)

Consensus market for Seahawks at 49ers — lines as of Wed, 9/9 · 7:04 PM CT
MarketConsensus
SpreadSEA -1.5 (open -1.5)
Total46.5
Moneyline (SEA / SF)-110 / -110
SF implied win probability50%
Implied team totals (SEA — SF)24.0 — 22.5

Devigged cross-book consensus, updated as lines move. See the power ratings for the model's implied line on any matchup.

Player projections

Seattle Seahawks · 22.5 proj pts
Drew Lock (QB) — 192 pass yds · 9 rush yds
Jaxon Smith-Njigba (WR) — 1 rush yds · 83 rec yds
Jadarian Price (RB) — 54 rush yds · 12 rec yds
San Francisco 49ers · 24.0 proj pts
Brock Purdy (QB) — 229 pass yds · 17 rush yds
Christian McCaffrey (RB) — 44 rush yds · 37 rec yds
Deebo Samuel Sr. (WR) — 4 rush yds · 41 rec yds

Research context, not a pick — every staked play is graded on the public ledger. How we grade.

Go deeper

The interactive matchup dashboard adds usage cores, opponent-defense-vs-position strips, offense identity, and the multi-book open→close board for this game. Forecast conditions are on the NFL slate.

More Week 12 games

← Week 11 · Week 13 → · Full 2026 schedule