Seattle Seahawks @ San Francisco 49ers — Prediction & Odds, NFL Week 12 2026

Sunday, November 29, 2026 · 4:25 PM ET · Levi's Stadium

Prediction: 49ers 23.5, Seahawks 23.5 (market-implied). The market gives the San Francisco 49ers a 51% chance to win. · Updated

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Every angle of Seahawks @ 49ers, on one screen.

Seahawks23.5win 49%
Market-implied score
49ers23.5win 51%
SpreadPK
Total47
Moneyline-110 / -115
  • The market-implied score next to the spread and total
  • Player projections against their prop lines, with the best price
  • What decides it: each passing matchup, protection and pace
  • Who is out and how much they play, and the best price on every side
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Seahawks vs 49ers prediction

Seattle Seahawks meet San Francisco 49ers on a level spread, with the game total at 47.

Moneylines sit at -110 for Seattle Seahawks and -115 for San Francisco 49ers, a devigged 51% win probability for San Francisco 49ers; splitting the spread and total leaves market-implied team totals of 23.5 for Seattle Seahawks and 23.5 for San Francisco 49ers.

The spread has moved from SF -1.5 to PK since it opened.

The Sport Stack's nflsim engine projects Seattle Seahawks — Drew Lock (QB) at 221 passing yards and 10 rushing yards, Jaxon Smith-Njigba (WR) at 2 rushing yards and 83 receiving yards; San Francisco 49ers — Brock Purdy (QB) at 240 passing yards and 19 rushing yards, Christian McCaffrey (RB) at 49 rushing yards and 35 receiving yards.

Kickoff is Sunday, November 29, 2026 · 4:25 PM ET, at Levi's Stadium, Seattle Seahawks take the extra rest, 14 days to 7.

New to these numbers? How devigging turns a price into a probability, how sportsbooks set these lines, what expected value means, and why to shop the number.

Consensus market

Consensus market for Seahawks at 49ers — lines as of Wed, 9/9 · 8:04 PM ET
MarketConsensus
SpreadPK (open SF -1.5)
Total47
Moneyline (SEA / SF)-110 / -115
SF implied win probability51%
Implied team totals (SEA — SF)23.5 — 23.5

Devigged cross-book consensus from the latest snapshot we hold, dated above. See the power ratings for the model's implied line on any matchup.

Seahawks and 49ers this season

Games before Week 12. Against the spread and over/under are graded against the consensus line.
TeamRecordAgainst the spreadOver/underPoints forPoints againstDays of rest
Seattle Seahawks5-43-4-24-522.418.014
San Francisco 49ers7-15-34-429.419.57

Seahawks' last 3 games: W 17-3 vs ARI · L 17-34 vs CHI · W 20-3 vs KC.

49ers' last 3 games: W 38-17 vs LV · L 20-29 @ ATL · W 23-17 vs WAS.

Player projections

Seattle Seahawks · 23.5 market-implied pts
Drew Lock (QB) — 221 pass yds · 10 rush yds
Jaxon Smith-Njigba (WR) — 2 rush yds · 83 rec yds
Zach Charbonnet (RB) — 43 rush yds · 13 rec yds
San Francisco 49ers · 23.5 market-implied pts
Brock Purdy (QB) — 240 pass yds · 19 rush yds
Christian McCaffrey (RB) — 49 rush yds · 35 rec yds
George Kittle (TE) — 53 rec yds · 4.7 rec

Research context, not a pick — every staked play is graded on the public ledger. How we grade.

What decides Seahawks @ 49ers, who is out and how much they play, the best price on every side, and every book's number.

Open the Seahawks @ 49ers matchup →

Kickoff weather and conditions are on the NFL slate.

More Week 12 games

← Week 11 · Week 13 → · Full 2026 schedule

Seahawks 2026 schedule

49ers 2026 schedule