Denver Broncos @ San Francisco 49ers — Final Score & Result, NFL Week 4 2026

Sunday, October 4, 2026 · 4:25 PM ET · Levi's Stadium

The full matchup dashboard

How this game played out, every angle on one screen.

Broncos14market had 22.8
Final
49ers24market had 25.8
SpreadSF -3
Total48.5
Moneyline+140 / -165
  • The market-implied score next to the spread and total
  • Player projections against their prop lines, with the best price
  • What decides it: each passing matchup, protection and pace
  • Who is out and how much they play, and the best price on every side

Game preview

The market makes San Francisco 49ers a 3-point favorite over Denver Broncos, with the game total at 48.5.

Moneylines sit at +140 for Denver Broncos and -165 for San Francisco 49ers, a devigged 60% win probability for San Francisco 49ers; splitting the spread and total leaves market-implied team totals of 22.8 for Denver Broncos and 25.8 for San Francisco 49ers.

The spread has moved from SF -2.5 to SF -3 since it opened and the total has moved from 46.5 to 48.5.

The Sport Stack's nflsim engine had projected Denver Broncos — Bo Nix (QB) at 206 passing yards and 17 rushing yards, J.K. Dobbins (RB) at 55 rushing yards and 9 receiving yards; San Francisco 49ers — Brock Purdy (QB) at 231 passing yards and 17 rushing yards, Christian McCaffrey (RB) at 60 rushing yards and 37 receiving yards.

Kickoff is Sunday, October 4, 2026 · 4:25 PM ET, at Levi's Stadium.

Final: San Francisco 49ers won 24-14; San Francisco 49ers covered the spread (SF -3) and the game went under the 48.5 total.

New to these numbers? How devigging turns a price into a probability, how sportsbooks set these lines, what expected value means, and why to shop the number.

Final

DEN 14 — SF 24

San Francisco 49ers covered the spread (SF -3) and the game went under the 48.5 total.

Consensus market (closing lines)

Consensus market for Broncos at 49ers — lines as of Sun, 10/4 · 4:20 PM ET
MarketConsensus
SpreadSF -3 (open SF -2.5)
Total48.5 (open 46.5)
Moneyline (DEN / SF)+140 / -165
SF implied win probability60%
Implied team totals (DEN — SF)22.8 — 25.8

Devigged cross-book consensus. See the power ratings for the model's implied line on any matchup.

Broncos and 49ers this season

Games before Week 4. Against the spread and over/under are graded against the consensus line.
TeamRecordAgainst the spreadOver/underPoints forPoints againstDays of rest
Denver Broncos2-12-11-220.023.37
San Francisco 49ers3-02-12-132.716.77

Broncos' last 3 games: W 30-26 vs LA · W 20-13 vs JAX · L 10-31 @ KC.

49ers' last 3 games: W 36-30 vs ARI · W 35-13 vs MIA · W 27-7 @ LA.

Pre-game injury report

Denver Broncos

Inactive: Sam Ehlinger (QB), Dallen Bentley (TE), Kage Casey (T), Tyler Onyedim (DT).

San Francisco 49ers

Inactive: Kurtis Rourke (QB), Jordan James (RB), Enrique Cruz Jr. (T), Ephesians Prysock (CB), James Thompson Jr. (DT).

Gameday inactives as of Sun, 10/4 · 3:22 PM ET.

Player projections

Denver Broncos · 22.8 market-implied pts
Bo Nix (QB) — 206 pass yds · 17 rush yds
J.K. Dobbins (RB) — 55 rush yds · 9 rec yds
Jaylen Waddle (WR) — 1 rush yds · 52 rec yds
San Francisco 49ers · 25.8 market-implied pts
Brock Purdy (QB) — 231 pass yds · 17 rush yds
Christian McCaffrey (RB) — 60 rush yds · 37 rec yds
George Kittle (TE) — 57 rec yds · 4.4 rec

Research context, not a pick — every staked play is graded on the public ledger. How we grade.

What decides Broncos @ 49ers, who is out and how much they play, the best price on every side, and every book's number.

Open the Broncos @ 49ers matchup →

Kickoff weather and conditions are on the NFL slate.

More Week 4 games

← Week 3 · Week 5 → · Full 2026 schedule

Broncos 2026 schedule

49ers 2026 schedule